Title : The proteasome inhibitor bortezomib augments anti-proliferative effects of mistletoe lectin-I and the PPAR-gamma agonist rosiglitazone in human melanoma cells.

Pub. Date : 2007 Jan-Feb

PMID : 17352234






1 Functional Relationships(s)
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1 RESULTS: At a concentration of 0.1 microg/ml bortezomib significantly reduced the proliferation rate of all melanoma cells to 1-13% of the control, which was mediated through increased apoptosis and inhibition of NFkappaB expression. Bortezomib nuclear factor kappa B subunit 1 Homo sapiens