Title : Stable adhesion and migration of human neutrophils requires phospholipase D-mediated activation of the integrin CD11b/CD18.

Pub. Date : 2007 May

PMID : 17346796






1 Functional Relationships(s)
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1 Thus, these data indicate that PLD-synthesised PtdOH stimulates the generation of PtdIns(4,5)P(2), which in turn mediates talin binding to, and activation of, CD11b/CD18 required for neutrophil stable adhesion and migration. ptdoh integrin subunit alpha M Homo sapiens