Pub. Date : 2007 Apr 5
PMID : 17343372
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Discovery of N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N"-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-aminoindazole-based orally active multitargeted receptor tyrosine kinase inhibitor. | 1H-Indazol-3-amine | ret proto-oncogene | Homo sapiens |
2 | In our continued efforts to search for potent and novel receptor tyrosine kinase (RTK) inhibitors as potential anticancer agents, we discovered, through a structure-based design, that 3-aminoindazole could serve as an efficient hinge-binding template for kinase inhibitors. | 1H-Indazol-3-amine | ret proto-oncogene | Homo sapiens |
3 | In our continued efforts to search for potent and novel receptor tyrosine kinase (RTK) inhibitors as potential anticancer agents, we discovered, through a structure-based design, that 3-aminoindazole could serve as an efficient hinge-binding template for kinase inhibitors. | 1H-Indazol-3-amine | ret proto-oncogene | Homo sapiens |