Title : Pharmacology of alpha-conotoxin MII-sensitive subtypes of nicotinic acetylcholine receptors isolated by breeding of null mutant mice.

Pub. Date : 2007 Jun

PMID : 17341654






2 Functional Relationships(s)
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1 The data indicate that one alpha-CtxMII-sensitive nAChR subtype, prevalent on wild-type dopaminergic terminals, has the lowest EC(50) for a nicotine-mediated function so far measured in mice. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 In conclusion, the gene deletion strategy enabled isolation of alpha6* subtypes, and these nAChR subtypes exhibited differential activation by nicotine and cytisine. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus