Title : Increased extracellular signal regulated kinases phosphorylation in the adrenal gland in response to chronic ACTH treatment.

Pub. Date : 2007 Mar

PMID : 17332532






2 Functional Relationships(s)
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1 We confirmed that ACTH increased adrenal weight and corticosterone levels when compared with control or dexamethasone-treated animals. Corticosterone proopiomelanocortin Homo sapiens
2 When ERKs activation was blocked by the use of a specific MEK inhibitor (PD98059), there was a decrease in ACTH-induced corticosterone release and PCNA expression. Corticosterone proopiomelanocortin Homo sapiens