Title : The selective neurotoxicity produced by 3-chloropropanediol in the rat is not a result of energy deprivation.

Pub. Date : 2007 Apr 11

PMID : 17321661






1 Functional Relationships(s)
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1 We were able to show that 3-CPD is a substrate for glutathione-S-transferase and also that, after bioactivation by alcohol dehydrogenase, it generates an irreversible inhibitor of glutathione reductase. alpha-Chlorohydrin glutathione-disulfide reductase Rattus norvegicus