| Protein Name | glutathione-disulfide reductase |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 116686 |
| Gene Symbol | Gsr |
| UniProt | F1LRE1 (F1LRE1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
577
Total Number of Articles : 1024 |
Description |
glutathione-disulfide reductase |
| Gene Summary |
Enables several functions, including glutathione binding activity; glutathione-disulfide reductase (NADPH) activity; and nucleotide binding activity. Involved in several processes, including response to iron(III) ion; response to ischemia; and response to vitamin A. Located in cytosol and mitochondrion. Used to study cataract and transient cerebral ischemia. Biomarker of several diseases, including Parkinsonism; acute kidney failure (multiple); hemorrhagic cystitis; myoglobinuria; and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in macular degeneration. Orthologous to human GSR (glutathione-disulfide reductase). [provided by Alliance of Genome Resources, Apr 2022] |
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