Title : Nelfinavir induces adipocyte insulin resistance through the induction of oxidative stress: differential protective effect of antioxidant agents.

Pub. Date : 2006

PMID : 17302375






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Enhancing cellular thiols with N-acetylcystein prevented the NFV-induced drop in reduced thiols and partially protected against the induction in HO-1, but failed to prevent insulin resistance or cleavage of poly ADP ribose polymerase (PARP), a process indicative of activation of pro-apoptotic caspases. Sulfhydryl Compounds heme oxygenase 1 Homo sapiens