Pub. Date : 2007 Feb 20
PMID : 17286973
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DNA polymerase beta catalytic efficiency mirrors the Asn279-dCTP H-bonding strength. | 2'-deoxycytidine 5'-triphosphate | DNA polymerase beta | Homo sapiens |
| 2 | Ternary complexes of wild type or mutant form of human DNA polymerase beta (pol beta) bound to DNA and dCTP substrates were studied by molecular dynamics (MD) simulations. | 2'-deoxycytidine 5'-triphosphate | DNA polymerase beta | Homo sapiens |
| 3 | Ternary complexes of wild type or mutant form of human DNA polymerase beta (pol beta) bound to DNA and dCTP substrates were studied by molecular dynamics (MD) simulations. | 2'-deoxycytidine 5'-triphosphate | DNA polymerase beta | Homo sapiens |
| 4 | The correlation coefficients show that the strength of the H-bond between dCTP and Asn279 is a strong predictor of the mutation-induced changes in the catalytic efficiency of pol beta. | 2'-deoxycytidine 5'-triphosphate | DNA polymerase beta | Homo sapiens |