Protein Name | DNA polymerase beta |
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Organism | Homo sapiens |
Gene ID | 5423 |
Gene Symbol | POLB |
UniProt | P06746 (DPOLB_HUMAN), B7Z1W5 (B7Z1W5_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
414
Total Number of Articles : 463 |
Description |
DNA polymerase beta |
Gene Summary |
The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011] |
synonyms |
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Properties | |