Title : Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation.

Pub. Date : 2007 Mar 23

PMID : 17255109






1 Functional Relationships(s)
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Protein Name
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1 c-Cbl binding likely targets Spry2 for ubiquitin-linked destruction, whereas the phosphatase binding and activity are necessary to dephosphorylate specific Ser/Thr residues. Threonine Cbl proto-oncogene Homo sapiens