Pub. Date : 2007 Aug
PMID : 17228340
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Brief RU 38486 treatment normalizes the effects of chronic stress on calcium currents in rat hippocampal CA1 neurons. | Calcium | carbonic anhydrase 1 | Rattus norvegicus |
| 2 | In the present study, we examined (i) whether unpredictable stress during 21 days affects calcium (Ca) currents of CA1 pyramidal neurons recorded on day 22; and (ii) if so, whether this change is normalized by treatment with the glucocorticoid receptor-antagonist RU 38486 during days 18-21. | Calcium | carbonic anhydrase 1 | Rattus norvegicus |
| 3 | In conclusion, the data indicate that chronic stress, RU 38486 treatment as well as acute rises in corticosterone level strongly modulate calcium influx into CA1 neurons. | Calcium | carbonic anhydrase 1 | Rattus norvegicus |