Title : BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein, is required for correct glycosylation and function of integrin beta1.

Pub. Date : 2007 Jan 23

PMID : 17227842






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Brefeldin A-inhibited guanine nucleotide-exchange proteins (BIG) 1 and BIG2 activate human ADP-ribosylation factors (ARF) 1 and ARF3 by catalyzing the replacement of ARF-bound GDP with GTP to regulate Golgi vesicular transport. Guanosine Diphosphate ADP ribosylation factor 1 Homo sapiens