Title : Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase.

Pub. Date : 2007 Jan

PMID : 17218638






1 Functional Relationships(s)
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1 Resolution of the crystal structure of PIM1 in complex with quercetagetin or two other flavonoids revealed a spectrum of binding poses and hydrogen-bonding patterns in spite of strong similarity of the ligands. Hydrogen Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens