Title : Iron chelation acutely stimulates fetal human intestinal cell production of IL-6 and VEGF while decreasing HGF: the roles of p38, ERK, and JNK MAPK signaling.

Pub. Date : 2007 Apr

PMID : 17204543






2 Functional Relationships(s)
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1 DFO stimulation resulted in a significant increase in epithelial cell IL-6 and VEGF production while yielding a decrease in HGF production (P<0.05). Deferoxamine interleukin 6 Homo sapiens
2 In conclusion, DFO acutely increases fetal human intestinal epithelial cell IL-6 and VEGF expression while causing an unexpected decrease in HGF expression and no detectable TNF-alpha production. Deferoxamine interleukin 6 Homo sapiens