Title : Contributions of reactive oxygen species and mitogen-activated protein kinase signaling in arsenite-stimulated hemeoxygenase-1 production.

Pub. Date : 2007 Jan 15

PMID : 17196236






2 Functional Relationships(s)
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1 Cooperation between ERK signaling and ROS generation was demonstrated by synergistic induction of HO-1 in cells co-treated with EGF and xanthine/xanthine oxidase resulting in a response nearly equivalent to that observed with arsenite. arsenite mitogen-activated protein kinase 1 Homo sapiens
2 These findings suggest that the ERK/MAPK activation is necessary but not sufficient for optimal arsenite-stimulated HO-1 induction. arsenite mitogen-activated protein kinase 1 Homo sapiens