Title : Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion.

Pub. Date : 2007 Feb

PMID : 17178380






1 Functional Relationships(s)
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1 We report herein that administration of the selective COX-2 inhibitor, celecoxib, significantly reduces the number of Gr1(+)CD11b(+) immature myeloid suppressor cells (IMSCs) during chemoprevention of 1,2-dimethylhydrazine diHCl-(1,2-DMH-) induction of large intestinal tumors in Swiss mice. Celecoxib integrin subunit alpha M Homo sapiens