Title : Downregulation of VEGF-A, STAT5 and AKT in acute myeloid leukemia blasts of patients treated with SU5416.

Pub. Date : 2006 Dec

PMID : 17169805






1 Functional Relationships(s)
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1 This provided the rationale for a multicenter clinical trial in patients with refractory AML with SU5416, a small molecule kinase inhibitor which blocks phosphorylation of c-kit, FLT3, VEGFR-1, VEGFR-2 (KDR) and VEGFR-3. Semaxinib fms related receptor tyrosine kinase 3 Homo sapiens