Title : Palladium-catalyzed functionalization of indoles with 2-acetoxymethyl-substituted electron-deficient alkenes.

Pub. Date : 2006 Dec 22

PMID : 17168610






2 Functional Relationships(s)
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1 It was found that for N-protected indoles the reaction proceeded smoothly in the presence of 5 mol % of Pd(acac)2 and 10 mol % of PPh3 at 80 degrees C in HOAc, while for N-unprotected indoles, the reaction was carried out by using 5 mol % of Pd(dba)2 or 2.5 mol % of Pd2(dba)3.CHCl3 with 10 mol % of 2,2"-bipyridine as the catalyst in toluene. Nitrogen caveolin 1 Homo sapiens
2 It was found that for N-protected indoles the reaction proceeded smoothly in the presence of 5 mol % of Pd(acac)2 and 10 mol % of PPh3 at 80 degrees C in HOAc, while for N-unprotected indoles, the reaction was carried out by using 5 mol % of Pd(dba)2 or 2.5 mol % of Pd2(dba)3.CHCl3 with 10 mol % of 2,2"-bipyridine as the catalyst in toluene. Nitrogen caveolin 1 Homo sapiens