Pub. Date : 2006 Dec 19
PMID : 17164333
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Through global phosphoproteome analysis, we identified a unique phosphosubstrate signature associated with each drug-resistant allele, including a shift in phosphorylation of two tyrosines (Tyr253 and Tyr257) in the ATP binding loop (P-loop) of BCR-ABL when Thr315 is Ile or Ala. | Isoleucine | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |