Title : IL-8 inhibits histamine release from human basophils induced by histamine-releasing factors, connective tissue activating peptide III, and IL-3.

Pub. Date : 1991 Sep 15

PMID : 1716285






3 Functional Relationships(s)
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1 IL-8 inhibits histamine release from human basophils induced by histamine-releasing factors, connective tissue activating peptide III, and IL-3. Histamine pro-platelet basic protein Homo sapiens
2 We now report the effect of IL-8 upon HRF-, connective tissue activating peptide III (CTAP III)-, and IL-3-induced histamine release from human basophils. Histamine pro-platelet basic protein Homo sapiens
3 Histamine release produced by two different HRF-containing chromatographic fractions (HRFvoid and HRFpeak 2) and purified CTAP-III (5 micrograms/ml) was inhibited by IL-8 in 10 of 12 donors, three of three donors, and seven of 10 donors, respectively. Histamine pro-platelet basic protein Homo sapiens