Protein Name pro-platelet basic protein
Organism Homo sapiens
Gene ID 5473
Gene Symbol


UniProt P02775 (CXCL7_HUMAN)
Relationships Total Number of functionally related compound(s) : 339
Total Number of Articles : 407

pro-platelet basic protein

Gene Summary

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]

  • platelet basic protein
  • C-X-C motif chemokine 7
  • CXC chemokine ligand 7
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