Title : Novel neuroprotective mechanisms of pramipexole, an anti-Parkinson drug, against endogenous dopamine-mediated excitotoxicity.

Pub. Date : 2007 Feb 28

PMID : 17161393






1 Functional Relationships(s)
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1 Pramipexole, a dopamine D2/D3 receptor agonist used clinically in the treatment of Parkinson disease, did not affect glutamate-induced calcium influx but blocked dopaminergic neuronal death induced by glutamate. Pramipexole dopamine receptor D2 Homo sapiens