Title : The labeling of lipoproteins for studies of cellular binding with a fluorescent lipophilic dye.

Pub. Date : 1991 May 15

PMID : 1716067






1 Functional Relationships(s)
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1 Mediation of binding by the LDL receptor is demonstrated by correspondence between the LDL receptor dissociation constant derived from this work and literature values; increased specific binding in lymphocytes cultured in lipoprotein-deficient media to up-regulate the LDL receptor; and decreased specific binding in lymphocytes cultured in the presence of 25-hydroxy cholesterol for 48 h to suppress the LDL receptor. 25-hydroxycholesterol low density lipoprotein receptor Homo sapiens