PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1716067-7 1991 Mediation of binding by the LDL receptor is demonstrated by correspondence between the LDL receptor dissociation constant derived from this work and literature values; increased specific binding in lymphocytes cultured in lipoprotein-deficient media to up-regulate the LDL receptor; and decreased specific binding in lymphocytes cultured in the presence of 25-hydroxy cholesterol for 48 h to suppress the LDL receptor. 25-hydroxycholesterol 357-379 low density lipoprotein receptor Homo sapiens 28-40