Title : Pioglitazone inhibits androgen production in NCI-H295R cells by regulating gene expression of CYP17 and HSD3B2.

Pub. Date : 2007 Mar

PMID : 17138841






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Pioglitazone inhibits androgen production in NCI-H295R cells by regulating gene expression of CYP17 and HSD3B2. Pioglitazone cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 Pioglitazone but not rosiglitazone inhibited the expression of the CYP17 and HSD3B2 genes. Pioglitazone cytochrome P450 family 17 subfamily A member 1 Homo sapiens
3 Likewise, pioglitazone repressed basal and 8-bromo-cAMP-stimulated activities of CYP17 and HSD3B2 promoter reporters in NCI-H295R cells. Pioglitazone cytochrome P450 family 17 subfamily A member 1 Homo sapiens