Pub. Date : 2007 Feb 2
PMID : 17134721
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | With a K(d) value for the Sec2:Sec4.GDP interaction of ca 70 microM and a maximal rate of GDP displacement of ca 15 s(-1), it is 100-1000-fold more effective than other proteins showing exchange activity towards Rabs (MSS4, DSS4, Vps9) and ca tenfold faster than Cdc25 as a Ras specific exchanger, although still 100-fold slower than the fastest systems studied so far, EF-Tu/Ef-Ts and Ran/RCC1. | Guanosine Diphosphate | Ras family guanine nucleotide exchange factor CDC25 | Saccharomyces cerevisiae S288C |
| 2 | With a K(d) value for the Sec2:Sec4.GDP interaction of ca 70 microM and a maximal rate of GDP displacement of ca 15 s(-1), it is 100-1000-fold more effective than other proteins showing exchange activity towards Rabs (MSS4, DSS4, Vps9) and ca tenfold faster than Cdc25 as a Ras specific exchanger, although still 100-fold slower than the fastest systems studied so far, EF-Tu/Ef-Ts and Ran/RCC1. | Guanosine Diphosphate | Ras family guanine nucleotide exchange factor CDC25 | Saccharomyces cerevisiae S288C |