Title : Novel n-3 fatty acid oxidation products activate Nrf2 by destabilizing the association between Keap1 and Cullin3.

Pub. Date : 2007 Jan 26

PMID : 17127771






1 Functional Relationships(s)
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1 These experiments provide a biochemical basis for the hypothesis that formation of J-ring compounds generated from oxidation of EPA and DHA in vivo can reach concentrations high enough to induce Nrf2-based cellular defense systems. Docosahexaenoic Acids NFE2 like bZIP transcription factor 2 Homo sapiens