Pub. Date : 2007 Feb
PMID : 17116690
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mutation of the SH2C domain tyrosine binding site led to constitutive PLC-gamma1 activation. | Tyrosine | phospholipase C gamma 1 | Homo sapiens |
| 2 | PLC-gamma1 constructs with mutations in tyrosine 509 and phenylalanine 510 in the sPHN domain no longer required an intact amino-terminal Src homology (SH2N) domain or phosphorylation of tyrosine 775 or 783 for activation. | Tyrosine | phospholipase C gamma 1 | Homo sapiens |
| 3 | PLC-gamma1 constructs with mutations in tyrosine 509 and phenylalanine 510 in the sPHN domain no longer required an intact amino-terminal Src homology (SH2N) domain or phosphorylation of tyrosine 775 or 783 for activation. | Tyrosine | phospholipase C gamma 1 | Homo sapiens |