Title : BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling.

Pub. Date : 2007 Jan

PMID : 17113272






1 Functional Relationships(s)
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1 Recently, the second vertebrate homologue of Legless, BCL9-2 (or B9L), was characterized and proposed to mediate Wnt signaling in a Pygopus-independent manner, by binding to a Tyrosine-142-phosphorylated form of beta-catenin. Tyrosine catenin beta 1 Homo sapiens