Title : Voriconazole, but not terbinafine, markedly reduces alfentanil clearance and prolongs its half-life.

Pub. Date : 2006 Nov

PMID : 17112806






1 Functional Relationships(s)
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1 OBJECTIVE: Alfentanil is a short-acting synthetic opioid analgesic, which is extensively metabolized, mainly by hepatic cytochrome P450 (CYP) 3A enzymes. Alfentanil cytochrome P450 family 3 subfamily A member 4 Homo sapiens