Pub. Date : 1991 Mar
PMID : 1711091
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effect of gamma-aminobutyric acid (GABA) on intracellular pH (pHi) was examined in the crayfish stretch-receptor neurone using H(+)-selective microelectrodes and a two-microelectrode voltage clamp. | gamma-Aminobutyric Acid | glucose-6-phosphate isomerase | Homo sapiens |
| 2 | The effect of gamma-aminobutyric acid (GABA) on intracellular pH (pHi) was examined in the crayfish stretch-receptor neurone using H(+)-selective microelectrodes and a two-microelectrode voltage clamp. | gamma-Aminobutyric Acid | glucose-6-phosphate isomerase | Homo sapiens |
| 3 | In the presence of 30 mmol l-1 HCO3- (pH 7.4), application of GABA (0.5 mmol l-1) produced a mean fall in pHi of 0.26 units. | gamma-Aminobutyric Acid | glucose-6-phosphate isomerase | Homo sapiens |
| 4 | Acetazolamide (0.1 mmol l-1) decreased the rate of fall of pHi caused by a step increase in CO2 partial pressure as well as by GABA, which indicates that the neurone contains carbonic anhydrase. | gamma-Aminobutyric Acid | glucose-6-phosphate isomerase | Homo sapiens |
| 5 | All these observations support the conclusion that the GABA-induced fall in pHi is due to a net efflux of HCO3- through the inhibitory anion channels. | gamma-Aminobutyric Acid | glucose-6-phosphate isomerase | Homo sapiens |