Pub. Date : 2007 Jan 16
PMID : 17107691
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Roles of nuclear receptors in the up-regulation of hepatic cholesterol 7alpha-hydroxylase by cholestyramine in rats. | Cholestyramine Resin | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |
| 2 | Nuclear receptors are involved in regulating the expression of cholesterol 7alpha-hydroxylase (CYP7A1), however, their roles in the up-regulation of CYP7A1 by cholestyramine (CSR) are still unclear. | Cholestyramine Resin | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |
| 3 | Nuclear receptors are involved in regulating the expression of cholesterol 7alpha-hydroxylase (CYP7A1), however, their roles in the up-regulation of CYP7A1 by cholestyramine (CSR) are still unclear. | Cholestyramine Resin | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |
| 4 | Nuclear receptors are involved in regulating the expression of cholesterol 7alpha-hydroxylase (CYP7A1), however, their roles in the up-regulation of CYP7A1 by cholestyramine (CSR) are still unclear. | Cholestyramine Resin | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |
| 5 | Nuclear receptors are involved in regulating the expression of cholesterol 7alpha-hydroxylase (CYP7A1), however, their roles in the up-regulation of CYP7A1 by cholestyramine (CSR) are still unclear. | Cholestyramine Resin | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |
| 6 | Cholestyramine raised hepatic levels of CYP7A1 mRNA and activity in both groups. | Cholestyramine Resin | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |
| 7 | These results suggest that cholestyramine up-regulates the expression of CYP7A1 independently via LXR- or FXR-mediated pathways in rats. | Cholestyramine Resin | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |