Pub. Date : 2007 Jan
PMID : 17097873
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Increased dihydropyrimidine dehydrogenase activity associated with mild toxicity in patients treated with 5-fluorouracil and leucovorin. | Leucovorin | dihydropyrimidine dehydrogenase | Homo sapiens |
| 2 | Patients with a high-normal DPD activity proved to be at risk of developing mild toxicity upon treatment with 5FU-leucovorin, suggesting an important role of DPD in the aetiology of toxicity associated with catabolites of 5FU. | Leucovorin | dihydropyrimidine dehydrogenase | Homo sapiens |
| 3 | Patients with a high-normal DPD activity proved to be at risk of developing mild toxicity upon treatment with 5FU-leucovorin, suggesting an important role of DPD in the aetiology of toxicity associated with catabolites of 5FU. | Leucovorin | dihydropyrimidine dehydrogenase | Homo sapiens |