Title : Strategies for construction of luteinizing hormone beta subunit analogs with carboxyl terminal extensions in non-primate, non-equid mammalian species.

Pub. Date : 2007 Jan 2

PMID : 17092639






4 Functional Relationships(s)
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1 Here we further review our previous analysis, aimed at determining whether LHbeta genes in non-primate, non-equid species inherently possess DNA sequences that encode CTP-like domains. Cytidine Triphosphate luteinizing hormone subunit beta Homo sapiens
2 Furthermore, DNA sequences from mammalian LHbeta genes can be aligned to maximize similarity with CGbeta genes in order to devise more refined strategies for construction of CTP-bearing LHbeta analogs as exemplified in the bovine case. Cytidine Triphosphate luteinizing hormone subunit beta Homo sapiens
3 Furthermore, DNA sequences from mammalian LHbeta genes can be aligned to maximize similarity with CGbeta genes in order to devise more refined strategies for construction of CTP-bearing LHbeta analogs as exemplified in the bovine case. Cytidine Triphosphate luteinizing hormone subunit beta Homo sapiens
4 Thus, mammalian LHbeta genes have DNA sequences that can be potentially expressed in order to construct CTP-bearing glycoprotein hormone analogs. Cytidine Triphosphate luteinizing hormone subunit beta Homo sapiens