Protein Name luteinizing hormone subunit beta
Organism Homo sapiens
Gene ID 3972
Gene Symbol

LHB

UniProt P01229 (LSHB_HUMAN), A0A0F7RQE6 (A0A0F7RQE6_HUMAN)
Relationships Total Number of functionally related compound(s) : 80
Total Number of Articles : 83
Description

luteinizing hormone subunit beta

Gene Summary

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]

synonyms
  • lutropin subunit beta
  • interstitial cell stimulating hormone, beta chain
  • luteinizing hormone beta polypeptide
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Properties