Title : [Effects of quercetin on angiotensin II induced interleukin-6 in vascular smooth muscle cells].

Pub. Date : 2006 Jul

PMID : 17059008






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1 [Effects of quercetin on angiotensin II induced interleukin-6 in vascular smooth muscle cells]. Quercetin interleukin 6 Rattus norvegicus
2 OBJECTIVE: To observe the effects of quercetin on angiotensin (Ang II) induced interleukin-6 (IL-6) in vascular smooth muscle cells (VSMCs). Quercetin interleukin 6 Rattus norvegicus
3 OBJECTIVE: To observe the effects of quercetin on angiotensin (Ang II) induced interleukin-6 (IL-6) in vascular smooth muscle cells (VSMCs). Quercetin interleukin 6 Rattus norvegicus
4 The production of IL-6 in supernatant of quercetin treated cultures was detected by ELISA. Quercetin interleukin 6 Rattus norvegicus
5 Quercetin inhibited the production of Ang II -induced IL-6 in the culture in a dose-dependent manner. Quercetin interleukin 6 Rattus norvegicus
6 Similarly, the result with RT-PCR indicated that the expression of IL-6 mRNA induced by Ang II for 24h was down-regulated by quercetin. Quercetin interleukin 6 Rattus norvegicus
7 CONCLUSION: It demonstrates that quercetin possesses a inhibition of Ang II-induced production of IL-6 in VSMCs. Quercetin interleukin 6 Rattus norvegicus
8 Moreover, quercetin also down regulates the expression of IL-6 mRNA, suggesting the action of quercetin on IL-6 release induced by Ang II in VSMCs may underlie its anti-inflammatory properties. Quercetin interleukin 6 Rattus norvegicus
9 Moreover, quercetin also down regulates the expression of IL-6 mRNA, suggesting the action of quercetin on IL-6 release induced by Ang II in VSMCs may underlie its anti-inflammatory properties. Quercetin interleukin 6 Rattus norvegicus
10 Moreover, quercetin also down regulates the expression of IL-6 mRNA, suggesting the action of quercetin on IL-6 release induced by Ang II in VSMCs may underlie its anti-inflammatory properties. Quercetin interleukin 6 Rattus norvegicus
11 Moreover, quercetin also down regulates the expression of IL-6 mRNA, suggesting the action of quercetin on IL-6 release induced by Ang II in VSMCs may underlie its anti-inflammatory properties. Quercetin interleukin 6 Rattus norvegicus