Title : Tumor necrosis factor-alpha-induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line.

Pub. Date : 2006 Nov

PMID : 17046548






1 Functional Relationships(s)
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1 The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor cerivastatin inhibited TNF-alpha-induced PAI-1 production by 59%, which was reversed by coincubation with mevalonic acid. Mevalonic Acid serpin family E member 1 Homo sapiens