Title : Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin.

Pub. Date : 2006 Nov 15

PMID : 17045234






1 Functional Relationships(s)
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1 Whereas 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE) is the best substrate for human eLOX3 (2.4 s(-1); at 30 microM substrate), mouse eLOX3 shows the highest turnover with 8R-HPETE (2.9 s(-1)) followed by 8S-HPETE (1.3 s(-1)). 8R-HpETE arachidonate lipoxygenase 3 Mus musculus