Pub. Date : 2006 Oct 25
PMID : 17041725
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Overexpression of alpha-synuclein in SH-SY5Y cells partially protected against oxidative stress induced by rotenone]. | Rotenone | synuclein alpha | Homo sapiens |
| 2 | Both SH-SY5Y and alpha-synuclein overexpressed SH-SY5Y (SH-SY5Y/Syn) cells were treated with various concentrations of rotenone for different time. | Rotenone | synuclein alpha | Homo sapiens |
| 3 | Compared with SH-SY5Y cells, SOD activity in SH-SY5Y/Syn cells was increased distinctly (P<0.05) and alpha-synuclein significantly attenuated rotenone-induced cell apoptosis. | Rotenone | synuclein alpha | Homo sapiens |
| 4 | These results suggest that the alpha-synuclein overexpression in SH-SY5Y cells has a tendency to partially resist oxidative stress induced by rotenone and this response may assist cell survival. | Rotenone | synuclein alpha | Homo sapiens |