Title : Reversibly stable thiopolyplexes for intracellular delivery of genes.

Pub. Date : 2006 Oct 27

PMID : 17028038






1 Functional Relationships(s)
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1 In this study, PHEA was firstly functionalised with ethylendiamine, obtaining a well defined copolymer with pendant primary amine groups (PHEA-EDA), to which N-succinimidyl 3-(2-pyridyldithio) propionate (SPDP) and 3-(carboxypropyl)trimethyl-ammonium chloride (CPTA) were linked in two subsequent steps, allowing the introduction of thiol and cationic groups respectively. ethylenediamine ectodysplasin A Homo sapiens