| Protein Name | ectodysplasin A |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1896 |
| Gene Symbol | EDA |
| UniProt | Q92838 (EDA_HUMAN), A0A0U5J797 (A0A0U5J797_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
379
Total Number of Articles : 248 |
Description |
ectodysplasin A |
| Gene Summary |
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Properties | |