Title : Mechanisms of disease: multiple endocrine neoplasia type 1-relation to chromatin modifications and transcription regulation.

Pub. Date : 2006 Oct

PMID : 17024155






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In this capacity menin is a regulator of expression of the cyclin-dependent-kinase inhibitors p18INK4C and p27Kip1; furthermore, menin serves as a co-activator of estrogen receptor mediated transcription, by recruiting methyltransferase activity to lysine 4 of histone 3 at the estrogen responsive TFF1(pS2) gene promoter. Lysine cyclin dependent kinase inhibitor 1B Homo sapiens