Title : Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation.

Pub. Date : 2007 Jan

PMID : 17020955






1 Functional Relationships(s)
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1 In human liver microsomes, involvement of CYP2D6, CYP1A2, CYP2C9, and CYP2C19 in diphenhydramine N-demethylation was confirmed by using P450 isozyme-specific inhibitors. Nitrogen cytochrome P450 family 2 subfamily C member 19 Homo sapiens