Pub. Date : 2006 Nov
PMID : 17019598
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Increased insulin secretory capacity but decreased insulin sensitivity after correction of iron overload by phlebotomy in hereditary haemochromatosis. | Iron | insulin | Homo sapiens |
2 | RESULTS: Normalisation of tissue iron stores resulted in an average 1.8-fold increase in the integrated area under the insulin curve during OGTT (p<0.0001), but no significant change in the area under the glucose curve (10% decrease, p=0.32). | Iron | insulin | Homo sapiens |
3 | CONCLUSIONS/INTERPRETATION: Insulin secretory capacity improves after normalisation of iron stores in subjects with hereditary haemochromatosis. | Iron | insulin | Homo sapiens |