Title : Motexafin gadolinium-induced cell death correlates with heme oxygenase-1 expression and inhibition of P450 reductase-dependent activities.

Pub. Date : 2007 Jan

PMID : 17018578






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We demonstrate that inhibition of HO1 reflects an interaction of MGd with NADPH-cytochrome P450 reductase, the electron donor for HO1, that results in diversion of reducing equivalents from heme oxidation to oxygen reduction. Oxygen heme oxygenase 1 Homo sapiens
2 We demonstrate that inhibition of HO1 reflects an interaction of MGd with NADPH-cytochrome P450 reductase, the electron donor for HO1, that results in diversion of reducing equivalents from heme oxidation to oxygen reduction. Oxygen heme oxygenase 1 Homo sapiens