Pub. Date : 2007 Feb
PMID : 17012367
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We now provide evidence that activation of c-Src is crucial in signaling thrombin-induced ICAM-1 expression via tyrosine phosphorylation of RelA/p65. | Tyrosine | coagulation factor II, thrombin | Homo sapiens |
2 | We also observed that thrombin induced tyrosine phosphorylation of RelA/p65, and this phosphorylation was lost upon inhibition of c-Src, consistent with the requirement of activated c-Src for interaction with RelA/p65. | Tyrosine | coagulation factor II, thrombin | Homo sapiens |