Title : No T-cell tyrosine protein kinase signalling or calcium mobilization after CD4 association with HIV-1 or HIV-1 gp120.

Pub. Date : 1990 Dec 6

PMID : 1701034






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In normal T cells, surface association of CD4 molecules with other CD4 molecules or other T-cell surface proteins, such as the T-cell antigen receptor, stimulates the activity of the p56lck tyrosine kinase, resulting in the phosphorylation of various cellular proteins at tyrosine residues. Tyrosine LCK proto-oncogene, Src family tyrosine kinase Homo sapiens