Pub. Date : 2006 Oct
PMID : 17010100
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phosphodiesterase 1B differentially modulates the effects of methamphetamine on locomotor activity and spatial learning through DARPP32-dependent pathways: evidence from PDE1B-DARPP32 double-knockout mice. | Methamphetamine | protein phosphatase 1, regulatory inhibitor subunit 1B | Mus musculus |
| 2 | Analysis of the response to d-methamphetamine on locomotor activity showed that the hyperactivity experienced by PDE1B mutant mice was blocked in PDE1B-/- x DARPP32-/- double-KO mice, consistent with participation of PDE1B and DARPP32 in the same pathway. | Methamphetamine | protein phosphatase 1, regulatory inhibitor subunit 1B | Mus musculus |
| 3 | Analysis of the response to d-methamphetamine on locomotor activity showed that the hyperactivity experienced by PDE1B mutant mice was blocked in PDE1B-/- x DARPP32-/- double-KO mice, consistent with participation of PDE1B and DARPP32 in the same pathway. | Methamphetamine | protein phosphatase 1, regulatory inhibitor subunit 1B | Mus musculus |