Title : Examination of two independent kinetic assays for determining the inhibition of carbonic anhydrases I and II: structure-activity comparison of sulfamates and sulfamides.

Pub. Date : 2006 Aug

PMID : 16999776






1 Functional Relationships(s)
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1 We compared a native and a non-native substrate in the context of inhibition of human carbonic anhydrases I and II by examining various sulfamate and sulfamide compounds in two kinetic assays: hydration of CO(2) and hydrolysis of 4-nitrophenylacetate. 4-nitrophenyl acetate carbonic anhydrase 1 Homo sapiens